and urban planning. One can assume that collecting "Big Data" is often accelerated with the introduction of "Big Bulls". This could only have been conducted in the streets of Pamplona as the feasibility of replicating this in a lab would be frowned upon by university "institutional review boards."

"Dr. Daniel Parisi set up cameras to study when and how a stampede begins. He already knew that loose crowds move fast and dense crowds slow. His research revealed an unexpected result when they observed how a crowd became both dense and faster."

Buried somewhere in this observational study is the comparison to individuals with disabilities. For decades they were paraded into society, followed, directed and controlled by naysayers and opponents of inclusion. The tables have turned, and those individuals with disabilities, along with advocates and their supporters are running over the dwindling members of society that enjoyed being behind and not in front of people determined to be included.

Make no mistake, the disability community has the speed, strength, muscle and temperament to give the charging bulls of Pamploma a run for their money. One can only assume that the naysayers are thinking, "They're gaining on us." •

ANCORA IMPARO

In his 87th year, the artist Michelangelo (1475 -1564) is believed to have said "Ancora imparo" (I am still learning). Hence, the name for my monthly observations and comments. – Rick Rader, MD, Editor-in-Chief, EP Magazine Director, Morton J. Kent Habilitation Center Orange Grove Center, Chattanooga, TN

WHAT'S HAPPENING

VACCINATED WOMEN PASS COVID-19 ANTIBODIES TO BREASTFEEDING BABIES

Women vaccinated against COVID-19 transfer SARS-CoV-2 antibodies to their breastfed infants, potentially giving their babies passive immunity against the coronavirus, according to University of Massachusetts Amherst research. The study, published in the journal Obstetrics & Gynecology, measured the immune response to the COVID-19 mRNA vaccine in both breast milk and the stools of breastfed infants.

“This research is the first to detect SARS-CoV-2 antibodies in stool samples from infants of vaccinated mothers,” says lead author Vignesh Narayanaswamy, a Ph.D. candidate in the breastmilk research lab of senior author Kathleen Arcaro, professor of environmental toxicology in the Department of Veterinary and Animal Sciences. “This is really important because women want to know whether their babies have these antibodies, and our study shows that antibodies are being transferred via breast milk. Providing this compelling evidence is motivation for women to continue breastfeeding after they receive the vaccine.”

Narayanaswamy notes another important takeaway: the antibodies were detected in infants regardless of age — from 1.5 months old to 23 months old. Thirty lactating women from across the U.S. — most of them healthcare workers — were enrolled in the study. They received the COVID-19 mRNA vaccine between January and April 2021. The women provided breast milk samples before they were vaccinated, across two to three weeks after their first vaccine dose and across three weeks after the second dose. They also gave samples of their blood, spotted on cards, 19 days after the first dose and 21 days after the second dose. Infant stool samples were col

lected 21 days after the mothers' second vaccination. Pre-pandemic samples of breast milk, dried blood spots and infant stools were used as controls for the study.

The samples were tested for receptor-binding domain (RBD)-specific immunoglobulin (Ig)A and IgG antibodies. In the breast milk samples, anti-RBD IgG antibodies were found to neutralize the protein spike of SARS-CoV-2, as well as four variants. A significant increase in cytokine levels also revealed the immune response in breast milk samples. AntiRBD IgG and anti-RBD IgA antibodies were detected in 33% and 30% of infant stool samples, respectively. The levels of antibodies correlated with the vaccine side effects the mother experienced.

MOTHER'S MILK: SARS-CoV-2 antibodies are transferred from vaccinated women to their breastfed infants, potentially giving the babies passive immunity against COVID-19 coronavirus, according to University of Massachusetts Amherst research.

“Women who did feel sick from the vaccine was associated with greater antibodies in the infant stool,” Arcaro says. “So you might have felt badly, but that was a benefit for your infant.” The study, Arcaro says, received no specific funding and was partially driven by the participants themselves, who were familiar with Arcaro’s wide-ranging breast milk research, including the New Moms Wellness Study and BRCA gene-mutation research that Narayanaswamy focuses on.

While lactating and pregnant women were urged to be vaccinated, no pregnant or breastfeeding women were included in the vaccine trials, Arcaro notes. Findings show that "even if you had COVID, there is a benefit for women to get the vaccine." The research team included Arcaro's UMass colleagues Dominique Alfandari, Brian Pentecost and Sallie Schneider; Dr. Corina Schoen, assistant professor of obstetrics and gynecology at UMass Chan Medical School-Baystate; and Ryan Baker, a UMass Amherst undergraduate student. •